研究について - 研究業績

2009年

  • Kondo K, Shintani S, Shibata R, Murakami H, Murakami R, Imaizumi T, Kitagawa S, Murohara T. Implantation of adipose-derived regenerative cells enhances ischemia-induced angiogenesis. Arterioscler. Thromb. Vasc. Biol. 2009; 29: 61-66.
  • Kondo M, Shibata R, Miura R, Shimano M, Kondo K, Li P, Ohashi T, Kihara S, Maeda N, Walsh K, Ouchi N, Murohara T. Caloric restriction stimulates revascularization in response to ischemia via adiponectin-mediated activation of eNOS. J. Biol. Chem. 2009; 284: 1718-1724.
  • Mori K, Amano M, Takefuji M, Kato K, Morita Y, Nishioka T, Matsuura Y, Murohara T, Kaibuchi K. Rho-kinase contributes to sustained RhoA activation through phosphorylation of p190A RhoGAP. J Biol. Chem. 2009; 284: 5067-5076.
  • Kato K, Fujimaki T, Yoshida T, Oguri M, Yajima K, Hibino T, Murohara T. Impact of matrix metalloproteinase-2 levels on long-term outcome following pharmacological or electrical cardioversion in patients with atrial fibrillation. Europace. 2009; 11: 332-337.
  • Nanasato M, Goto N, Isobe S, Unno K, Hirayama H, Sato T, Matsuoka S, Nagasaka T, Tominaga Y, Uchida K, Murohara T. Restored cardiac conditions and left ventricular function after parathyroidectomy in a hemodialysis patient. Circ. J. 2009.
  • Yoshida N, Yamada T, Murakami Y, Okada T, Ninomiya Y, Toyama J, Yoshida Y, Tsuboi N, Muto M, Inden Y, Hirai M, Murohara T. Vagal modification can also help prevent late recurrence of atrial fibrillation after segmental pulmonary vein isolation. Circ. J. 2009; 73: 632-638.
  • Miyagi M, Ishii H, Murakami R, Isobe S, Hayashi M, Amano T, Arai K, Ohashi T, Uetani T, Matsubara T, Murohara T. Impact of long-term statin treatment on coronary plaque composition at angiographically severe lesions: A nonrandomized study of the history of long-term statin treatment before coronary angioplasty. Clin. Ther. 2009; 31: 64-73.
  • Shibata R, Ouchi N, Murohara T. Adiponectin and cardiovascular disease. Circ. J. 2009; 73: 608-614. (Review).
  • Morikawa S, Sone T, Tsuboi H, Mukawa H, Morishima I, Uesugi M, Morita Y, Numaguchi Y, Okumura K, Murohara T. Renal protective effects and the prevention of contrast-induced nephropathy by atrial natriuretic peptide. J. Am. Coll. Cardiol. 2009; 53: 1040-1046.
  • Murohara T. Autologous adipose tissue as a new source of progenitor cells for therapeutic angiogenesis. J. Cardiol. 2009; 53: 155-163. (Review).
  • Aoyama T, Takeshita K, Kikuchi R, Yamamoto K, Cheng XW, Liao JK, Murohara T. Gamma-secretase inhibitor reduces diet-induced atherosclerosis in apolipoprotein E-deficient mice. Biochem. Biophys. Res. Commun. 2009.
  • Uetani T, Amano T, Kumagai S, Ando H, Yokoi K, Yoshida T, Kato B, Kato M, Marui N, Nanki M, Matsubara T, Ishii H, Izawa H, Murohara T. Intracoronary electrocardiogram recording with a bare-wire system: perioperative ST-segment elevation in the intracoronary electrocardiogram Is associated with myocardial injury after elective coronary stent implantation. JACC. Cardiovasc. Interv. 2009; 2: 127-135.
  • Shimano M, Shibata R, Inden Y, Yoshida N, Uchikawa T, Tsuji Y, Murohara T. Reactive oxidative metabolites are associated with atrial conduction disturbance in patients with atrial fibrillation. Heart Rhythm. 2009; 6: 935-940.
  • Yamada T, Yoshida N, Murakami Y, Okada T, Yoshida Y, Muto M, Inden Y, Murohara T. Vagal modification can be a valid predictor of late recurrence of paroxysmal atrial fibrillation independent of the pulmonary vein Isolation technique. Circ J. 2009.
  • Yoshikawa D, Isobe S, Umeda H, Kawai T, Shimizu T, Yamashita K, Ishii H, Murohara T. Three-year prognosis of Japanese patients with ST-elevation myocardial infarction treated with sirolimus-eluting stents. Coron Artery Dis. 2009.
  • Unno K, Shibata R, Izawa H, Hirashiki A, Murase Y, Yamada T, Kobayashi M, Noda A, Nagata K, Ouchi N, Murohara T. Adiponectin acts as a positive indicator of left ventricular diastolic dysfunction in patients with hypertrophic cardiomyopathy. Heart. 2009. (in press).
  • Murohara T, Shintani S, Kondo T. Autologous adipose-derived regenerative cells for therapeutic angiogenesis. Curr. Pharm. Des. 2009; 15: 2784-2790.
  • Miyagi M, Ishii H, Murakami R, Isobe S, Hayashi M, Amano T, Arai K, Yoshikawa D, Ohashi T, Uetani T, Yasuda Y, Matsuo S, Matsubara T, Murohara T. Impact of renal function on coronary plaque composition. Nephrol. Dial. Transplant. 2009.

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2008年

  • Li P, Kondo T, Numaguchi Y, Kobayashi K, Aoki M, Inoue N, Murohara T. Role of bradykinin, nitric oxide and angiotensin II type 2 receptor in imidapril-induced angiogenesis. Hypertension. 2008; 51: 252-258.
  • Aoyama T, Ishii H, Toriyama T, Takahashi H, Kasuga H, Murakami R, Amano T, Uetani T, Yasuda Y, Yuzawa Y, Maruyama S, Matsuo S, Matsubara T, Murohara T. Sirolimus-eluting stents versus bare metal stents for coronary intervention in Japanese patients with renal failure on hemodialysis. Circ. J. 2008; 72: 56-60.
  • Amano T, Matsubara T, Uetani T, Nanki M, Marui N, Kato M, Yoshida T, Arai K, Yokoi K, Ando H, Kumagai S, Ishii H, Izawa H, Hotta N, Murohara T. Abnormal glucose regulation is associated with lipid rich coronary plaque: relationship to insulin resistance. JACC. Cardiovasc. Imaging. 2008; 1: 39-45.
  • Kitamura T, Asai N, Enomoto A, Maeda K, Kato T, Ishida M, Jiang P, Watanabe T, Usukura J, Kondo T, Costantini F, Murohara T, Takahashi M. Regulation of VEGF-mediated angiogenesis by the Akt/PKB substrate Girdin. Nat. Cell Biol. 2008; 10: 329-337.
  • Shimano M, Tsuji Y, Inden Y, Kitamura K, Uchikawa T, Harata S, Nattel S, Murohara T. Pioglitazone, a peroxisome proliferator-activated receptor-gamma activator, attenuates atrial fibrosis and atrial fibrillation promotion in rabbits with congestive heart failure. Heart Rhythm. 2008; 5: 451-459.
  • Ishii H, Kumada Y, Toriyama T, Aoyama T, Takahashi H, Yamada S, Yasuda Y, Yuzawa Y, Maruyama S, Matsuo S, Matsubara T, Murohara T. Cilostazol improves long-term patency after percutaneous transluminal angioplasty in hemodialysis patients with peripheral artery disease. Clin. J. Am. Soc. Nephrol. 2008; 3: 1034-1040.
  • Yamada T, Murakami Y, Okada T, Yoshida N, Toyama J, Yoshida Y, Tsuboi N, Inden Y, Hirai M, Murohara T. Plasma brain natriuretic Peptide level after hybrid therapy with pulmonary vein isolation and antiarrhythmic drugs for atrial fibrillation. Int. Heart J. 2008; 49: 143-151.
  • Shibata R, Numaguchi Y, Matsushita K, Sone T, Kubota R, Ohashi T, Ishii M, Kihara S, Walsh K, Ouchi N, Murohara T. Usefulness of adiponectin to predict myocardial salvage following successful reperfusion in patients with acute myocardial infarction. Am. J. Cardiol. 2008; 101: 1712-1715.
  • Shimano M, Inden Y, Tsuji Y, Kamiya H, Uchikawa T, Shibata R, Murohara T. Circulating homocysteine levels in patients with radiofrequency catheter ablation for atrial fibrillation. Europace. 2008; 10: 961-966.
  • Uetani T, Amano T, Ando H, Yokoi K, Arai K, Kato M, Marui N, Nanki M, Matsubara T, Ishii H, Izawa H, Murohara T. The correlation between lipid volume in the target lesion, measured by integrated backscatter intravascular ultrasound, and post-procedural myocardial infarction in patients with elective stent implantation. Eur. Heart J. 2008; 29: 1714-1720.
  • Shimano M, Shibata R, Tsuji Y, Kamiya H, Uchikawa T, Harata S, Muto M, Ouchi N, Inden Y, Murohara T. Circulating adiponectin levels in patients with atrial fibrillation. Circ. J. 2008; 72: 1120-1124.
  • Kumada Y, Aoyama T, Ishii H, Tanaka M, Kawamura Y, Takahashi H, Toriyama T, Aoyama T, Yuzawa Y, Maruyama S, Matsuo S, Murohara T. Long-term outcome of percutaneous transluminal angioplasty in chronic haemodialysis patients with peripheral arterial disease. Nephrol. Dial. Transplant. 2008; 23: 3996-4001.
  • Sugiura T, Kondo T, Kureishi-Bando Y, Numaguchi Y, Yoshida O, Dohi Y, Kimura G, Ueda R, Rabelink TJ, Murohara T. Nifedipine improves endothelial function: role of endothelial progenitor cell. Hypertension. 2008; 52: 491-498.
  • Isobe S, Sato K, Sugiura K, Mimura T, Kobayashi M, Meno C, Kato M, Ishii H, Murohara T. Feasibility of intravenous administration of landiolol hydrochloride for multislice computed tomography coronary angiography. Circ. J. 2008; 72: 1814-1820.
  • Kado M, Lee JK, Hidaka K, Miwa K, Murohara T, Kasai K, Saga S, Morisaki T, Ueda Y, Kodama I. Paracrine factors of vascular endothelial cells facilitate cardiomyocyte differentiation of mouse embryonic stem cells. Biochem. Biophys. Res. Commun. 2008; 377: 413-418.
  • Matoba S, Tatsumi T, Murohara T, Imaizumi T, Katsuda Y, Ito M, Saito Y, Uemura S, Suzuki H, Fukumoto S, Yamamoto Y, Onodera R, Teramukai S, Fukushima M, Matsubara H; TACT Follow-up Study Investigators. Long-term clinical outcome after intramuscular implantation of bone marrow mononuclear cells (Therapeutic Angiogenesis by Cell Transplantation [TACT] trial) in patients with chronic limb ischemia. Am. Heart J. 2008; 156: 1010-1018.
  • Ishii H, Kumada Y, Toriyama T, Aoyama T, Takahashi H, Amano T, Yasuda Y, Yuzawa Y, Maruyama S, Matsuo S, Matsubara T, Murohara T. Aortic valvular calcification predicts restenosis after implantation of drug-eluting stents in patients on chronic haemodialysis. Nephrol. Dial. Transplant. 2008.
  • Ishii H, Amano T, Matsubara T, Murohara T. Pharmacological intervention for prevention of left ventricular remodeling and improving prognosis in myocardial infarction. Circulation. 2008; 118: 2710-2718.

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2007年

  • Shimizu K, Ito A, Lee JK, Yoshida T, Miwa K, Ishiguro H, Numaguchi Y, Murohara T, Kodama I, Honda H. Construction of multilayered cardiomyocyte sheets using magnetite nanoparticles and magnetic force. Biotechnol. Bioeng. 2007; 96: 803-809.
  • Inoue N, Kondo T, Kobayashi K, Aoki M, Numaguchi Y, Shibuya M, Murohara T. Therapeutic angiogenesis using novel vascular endothelial growth factor-E/human placental growth factor chimera genes. Arterioscler. Thromb. Vasc. Biol. 2007; 27: 99-105.
  • Kajiguchi M, Kondo T, Izawa H, Kobayashi K, Yamamoto K, Shintani S, Numaguchi Y, Naoe T, Takamatsu J, Komori K, Murohara T. Safety and efficacy of autologous progenitor cell transplantation for therapeutic angiogenesis in patients with critical limb ischemia. Circ. J. 2007; 71: 196-201.
  • Imai H, Numaguchi Y, Ishii M, Kubota R, Yokouchi K, Ogawa Y, Kondo T, Okumura K, Murohara T. Prostacyclin synthase gene transfer inhibits neointimal formation by suppressing PPARdelta expression. Atherosclerosis. 2007: 195: 322-332.
  • Takefuji M, Mori K, Morita Y, Arimura N, Nishimura T, nakayama M, Hoshino M, Iwamatsu A, Murohara T, kaibuchi K, Amano M. Rro-kinase modulates the function of STEF, a Rac GEF, through its phosphorylation. Biochem. Biophys. Res. Commun. 2007; 355: 788-794.
  • Cheng XW, Kuzuya M, Nakamura K, Maeda K, Tsuzuki M, Kim W, Sasaki T, Liu Z, Inoue N, Kondo T, Jin H, Numakuchi Y, Okumura K, Yokota M, Iguchi A, Murohara T. Mechanisms underlying the impairment of ischemia-induced neovascularization in MMP-2-deficient mice. Circ. Res. 2007; 100: 904-913.
  • Amano T, Matsubara T, Uetani T, Nanki M, Marui N, Kato M, Arai K, Yokoi K, Ando H, Ishii H, Izawa H, Murohara T. Impact of metabolic syndrome on tissue characteristics of angiographically mild to moderate coronary lesions: Integrated backscatter intravascular ultrasound study. J. Am. Coll. Cardiol. 2007; 49: 1149-1156.
  • Okada T, Yamada T, Murakami Y, Yoshida N, Ninomiya Y, Shimizu T, Toyama J, Yoshida Y, Ito T, Tsuboi N, Kondo T, Inden Y, Hirai M, Murohara T. Prevalence and severity of left atrial edema detected by electron beam tomography early after pulmonary vein ablation. J. Am. Coll. Cardiol. 2007 49: 1436-1442.
  • Ichihara S, Yamada Y, Ichihara G, Nakajima T, Li P, Kondo T, Gonzales FJ, Murohara T. A role for the aryl hydrocarbon receptor in regulation of ischemia-induced angiogenesis. 2007. Arterioscler. Thromb. Vasc. Biol. 2007; 27: 1297-1304.
  • Mitsuhashi H, Yatsuya H, Tamakoshi K, Matsushita K, Otsuka R, Wada K, Sugiura K, Takefuji S, Hotta Y, Kondo T, Murohara T, Toyoshima H. Adiponectin level and left ventricular hypertrophy in Japanese men. Hypertension. 2007; 49: 1448-1454.
  • Shimano M, Tsuji Y, Yoshida Y, Inden Y, Tsuboi N, Itoh T, Suzuki H, Muramatsu T, Okada T, Harata S, Yamada T, Hirayama H, Nattel S, Murohara T. Acute and chronic effects of cardiac resynchronization in patients developing heart failure with long-term pacemaker therapy for acquired complete atrioventricular block. Europace. 2007; 9: 869-874.
  • Nakamura T, Torimura T, Sakamoto M, Hashimoto O, Taniguchi E, Inoue K, Sakata R, Kumashiro R, Murohara T, Ueno T, Sata M. Significance and Therapeutic Potential of Endothelial Progenitor Cell Transplantation in a Cirrhotic Liver Rat Model. Gastroenterology. 2007; 133: 91-107.
  • Saito Y, Sasaki K, Katsuda Y, Murohara T, Takeshita Y, Okazaki T, Arima K, Katsuki Y, Shintani S, Shimada T, Akashi H, Ikeda H, Imaizumi T. Effect of autologous bone marrow cell transplantation on ischemic ulcer in patients with Burger’s disease. Circ. J. 2007; 71: 1187-1192.
  • Yamada T, Murakami Y, Okada T, Yoshida N, Toyama J, Yoshida Y, Tsuboi N, Inden Y, Hirai M, Murohara T. Plasma brain natriuretic peptide level after radiofrequency catheter ablation of paroxysmal, persistent, and permanent atrial fibrillation. Europace. 2007; 9: 770-774.
  • Yamada T, Kondo T, Numaguchi Y, Tsuzuki M, Matsubara T, Manabe I, Sata M, Nagai R, Murohara T. Angiotensin II Receptor Blocker Inhibits Neointimal Hyperplasia Through Regulation of Smooth Muscle-like Progenitor Cells. Arterioscler. Thromb. Vasc. Biol. 2007; 27: 2363-2369.
  • Yamada T, Murakami Y, Okada T, Yoshida N, Toyama J, Yoshida Y, Tsuboi N, Inden Y, Hirai M, Murohara T. Pulmonary vein antrum not always coaxial to the pulmonary vein: a dimensional pitfall to the circumferential isolation technique. Circ. J. 2007; 71: 1430-1436.
  • Shibata R, Ouchi N, Walsh K, Murohara T. The potential of adiponectin as a cardioprotective agent. Future Cardiol. 2007; 3: 647-656.

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2006年

  • Yokoyama S, Fukuda N, Li Y, Hagikura K, Takayama T, Kunimoto S, Honye J, Saito S, Wada M, Satomi A, Kato M, Mugishima H, Kusumi Y, Mitsumata M, Murohara T. A strategy of retrograde injection of bone marrow mononuclear cells into the myocardium for the treatment of ischemic heart disease. J. Mol. Cell. Cardiol. 2006; 40: 24-34.
  • Murakami H, Murakami R, Kambe F, Cao X, Takahashi R, Asai T, Hirai T, Numaguchi Y, Okumura K, Seo H, Murohara T. Fenofibrate activates AMPK and increases eNOS phosphorylation in HUVEC. Biochem. Biophys. Res. Commun. 2006; 341: 973-978.
  • Ishii H, Ichimiya S, Kanashiro M, Amano T, Matsubara T, Murohara T. Effects of intravenous nicorandil before reperfusion for acute myocardial infarction in patients with stress hyperglycemia. Diabetes Care. 2006; 29: 202-206.
  • Matsushita K, Yatsuya H, Tamakoshi K, Wada K, Otsuka R, Takefuji S, Sugiura K, Kondo T, Murohara T, Toyoshima H. Comparison of circulating adiponectin and proinflammatory markers regarding their association with metabolic syndrome in Japanese men. Arterioscler. Thromb. Vasc. Biol. 2006; 26: 871-876.
  • Taniguchi E, Kin M, Torimura T, Nakamura T, Kumemura M, Hanada S, Hisamoto T, Yoshida T, Kawaguchi T, Baba S, Maeyama M, Koga H, Harada M, Kumashiro R, Ueno T, Ikeda H, Imaizumi T, Murohara T, Sata M. Endothelial progenitor cell transplantation improves the outcome following liver injury in mice. Gastroenterology. 2006; 130: 521-531.
  • Shintani S, Kusano K, Ii M, Iwakura A, Heyd L, Curry C, Wecker A, Gavin M, Ma H, Kearney M, Silver M, Thorne T, Murohara T, Losordo DW. Synergistic effect of combined intramyocardial CD34 cells and VEGF-2 gene therapy post-myocardial infarction. Nat. Clin. Pract. Cardiovasc. Med. 2006; 3(Suppl.): S123-S128.
  • Amano T, Matsubara T, Izawa H, Torigoe M, Yoshida T, Hamaguchi Y, Ishii H, Miura M, Hayashi Y, Ogawa Y, Murohara T. Impact of plasma aldosterone levels for prediction of in-stent restenosis. Am. J. Cardiol. 2006; 97: 785-788.
  • Asai T, Okumura K, Takahashi R, Matsui H, Numaguchi Y, Murakami H, Murakami R, Murohara T. Peroxisome proliferators-activated receptor a activation, in addition to carnitine supplementation, rescues the detrimental lipotoxic cardiomyopathy due to disorder of fatty acid oxidation in a murine model of systemic carnitine deficiency. Cardiovasc. Res. 2006; 70: 566-577.
  • Yamada T, Murakami Y, Okada T, Okamoto M, Shimizu T, Toyama J, Yoshida Y, Tsuboi N, Ito T, Muto M, Kondo T, Inden Y, Hirai M, Murohara T. Incidence, location, and cause of recovery of electrical connections between the pulmonary veins and the left atrium after pulmonary vein isolation. Europace. 2006; 8: 182-188.
  • Egami K, Murohara T, Aoki M, Matsuishi T. Ischemia-induced angiogenesis: role of inflammatory response mediated by P-selectin. J. Leukoc. Biol. 2006; 79: 971-976.
  • Kobayashi K, Kondo T, Inoue N, Aoki M, Mizuno M, Komori K, Yoshida J, Murohara T. Combination therapy using angiopoietin-1 plasmid gene and autologous bone marrow cell implantation promotes functional angiogenesis. Arterioscler. Thromb. Vasc. Biol. 2006; 26: 1465-1472.
  • Yamada T, Murakami Y, Okada T, Okamoto M, Shimizu T, Toyama J, Yoshida Y, Tsuboi N, Ito T, Muto M, Kondo T, Inden Y, Hirai M, Murohara T. Usefulness of esophageal leads for determining the strategy of pulmonary vein ablation to avoid complications associated with the esophagus. Am. J. Cardiol. 2006; 97: 1494-1497.
  • Yamada T, Murakami Y, Okada T, Okamoto M, Shimizu T, Toyama J, Yoshida Y, Tsuboi N, Ito T, Muto M, Kondo T, Inden Y, Hirai M, Murohara T. Plasma atrial natriuretic peptide and brain natriuretic peptide levels after radiofrequency catheter ablation of atrial fibrillation. Am. J. Cardiol. 2006; 97: 1741-1744.
  • Numaguchi Y, Sone T, Okumura K, Morita Y, Kubota R, Yokouchi K, Imai H, Harada M, Kondo T, Murohara T. The impact of the capability of circulating progenitor cell to differentiate on myocardial salvage in patients with primary acute myocardial infarction. Circulation. 2006; 114: I114-I119.
  • Murase Y, Narita Y, Kagami H, Miyamoto K, Ueda Y, Ueda M, Murohara T. Evaluation of compliance and stiffness of decellularized tissues as scaffolds for tissue-engineered small caliber vascular grafts using intravascular ultrasound. ASAIO J. 2006; 52: 450-455.
  • Yokouchi K, Numaguchi Y, Okumura K, Ishii M, Kubota R, Imai H, Murakami R, Kondo T, Murohara T. l-Caldesmon regulates proliferation and migration of vascular smooth muscle cells and inhibits neointimal formation after angioplasty. Arterioscler. Thromb. Vasc. Biol. 2006; 26: 2231-2237.
  • Yasuma F, Murohara T, Hayano J. Long-term efficacy of acetazolamide on Cheyne-Stokes respiration in congestive heart failure. Am. J. Respir. Crit. Care Med. 2006; 174: 479.
  • Izawa H, Kondo T, Usui A, Yamamoto K, Shintani S, Inden Y, Isobe S, Unno K, Kajiguchi M, Noda A, Yokota M, Takamatsu J, Ueda Y, Komori K, Murohara T. Clinical Protocol: Angiogenesis by Intramyocardial Injection of Autologous Bone Marrow Mononuclear Cells in Patients with Severe Coronary Artery Disease. TACT-NAGOYA-HEART. Circ. J. 2006; 70: 1180-1183.
  • Shimano M, Inden Y, Yoshida Y, Tsuji Y, Tsuboi N, Okada T, Yamada T, Murakami Y, Takada Y, Hirayama H, Murohara T. Does RV Lead Positioning Provide Additional Benefit to Cardiac Resynchronization Therapy in Patients with Advanced Heart Failure? Pacing Clin Electrophysiol. 2006; 10: 1069-1074.

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2005年

  • Yoshida O, Hirayama H, Nanasato M, Watanabe T, Murohara T. The angiotensin II receptor blocker candesartan cilexetil reduces neointima proliferation after coronary stent implantation: a prospective randomized study under intravascular ultrasound guidance. Am. Heart J. 2005; 149: e2-e6.
  • Takahashi R, Okumura K, Asai T, Hirai T, Murakami H, Murakami R, Numaguchi Y, Matsui H, Ito M, Murohara T. Dietary fish oil attenuates cardiac hypertrophy in lipotoxic cardiomyopathy due to systemic carnitine deficiency. Cardiovasc. Res. 2005; 68: 213-223.
  • Ishii H, Ichimiya S, Kanashiro M, Amano T, Imai K, Murohara T, Matsubara T. The impact of a single intravenous administration of nicorandil before reperfusion in patients with ST-segment elevation myocardial infarction. Circulation. 2005; 112: 1284-1288.
  • Lee M, Aoki M, Kondo T, Okumura K, Komori K, Murohara T. Therapeutic angiogenesis with intramuscular injection of low dose recombinant granulocyte-colony stimulating factor. Arterioscler. Thromb. Vasc. Biol. 2005; 25: 2535-2541.

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2004年

  • Numaguchi Y, Okumura K, Harada M, Naruse K, Yamada M, Osanai H, Matsui H, Ito M, Murohara T. Catheter-based prostacyclin synthase gene transfer prevents in-stent restenosis in rabbit atheromatous arteries. Cardiovasc. Res. 2004; 61: 177-185.
  • Takeshita K, Fujimori T, Kurotaki Y, Honjo H, Tsujikawa H, Yasui K, Lee JH, Kamiya K, Kitaichi K, Ito M, Kondo T, Iino S, Yamamoto K, Inden Y, Hirai M, Murohara T, Kodama I, Nabeshima Y. Sinoatrial node dysfunction and early unexpected death of mice with a defect of klotho gene expression. Circulation. 2004; 109: 1776-1782.
  • Kondo T, Hayashi M, Kinoshita K, Kobayashi K, Iino S, Inden Y, Murohara T. Smoking cessation rapidly increases endothelial progenitor cells in peripheral blood in chronic smokers. Arterioscler. Thromb. Vasc. Biol. 2004; 24: 1442-1447.
  • Murohara T, Ikeda H, Otsuka Y, Aoki M, Haramaki N, Katoh A, Takajo Y, Imaizumi T. Inhibition of platelet adherence to mononuclear cells by a-tocopherol: Role of P-selectin. Circulation. 2004; 110: 141-148.
  • Shimada T, Takeshita Y, Murohara T, Sasaki K, Egami K, Shintani S, Katsuda Y, Ikeda H, Nabeshima Y, Imaizumi T. Angiogenesis and vasculogenesis are impaired in precocious aging Klotho mouse. Circulation. 2004; 110: 1148-1155.
  • Maeda K, Murakami H, Yoshida R, Ichihara M, Abe A, Hirai M, Murohara T, Takahashi M. Biochemical and biological responses induced by coupling of Gab1 to phosphatidylinositol 3-kinase in RET-expressing cells. Biochem. Biophys. Res. Commun. 2004; 323: 345-354.
  • Yamamoto K, Kondo T, Suzuki S, Izawa H, Kobayashi M, Emi N, Komori K, Naoe T, Takamatsu J, Murohara T. Molecular evaluation of endothelial progenitor cells in patients with ischemic limbs: therapeutic effect by stem cell transplantation. Arterioscler. Throm. Vasc. Biol. 2004; 24: e192-e196.
  • Aoki M, Yasutake M, Murohara T. Derivation of functional endothelial progenitor cells from human umbilical cord blood mononuclear cells isolated by a novel cell filtration device. Stem Cells. 2004; 22: 994-1002.
  • Kondo T, Kobayashi K, Murohara T. Nitric oxide signaling during myocardial angiogenesis. Mol. Cell. Biochem. 2004; 264: 25-34.

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